From Biloxi to Jackson to Greenville to Tupelo, and more.
The best marathons in Mississippi offer a mix of fast, flat courses, really hot ones, and scenic Southern charm.
Whether you’re chasing a PB or running for fun, you can enjoy the beauty as you wind through historic towns, enormous rivers, and picturesque foliage.
If you’re looking for your next race, this guide covers the top marathons in the state, highlighting unique features, course details, and what makes each one special.
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What are the Best Marathons in Mississippi?
Here are the best marathons in Mississippi:
Mississippi Gulf Coast Marathon
Biloxi | Dec 14, 2025
Course Type: Very Flat
Elevation Gain: 140 feet (42m)
Participants: 615 Finishers
Price: $181.20
The Mississippi Gulf Coast Marathon delivers a scenic, point-to-point race along the Gulf of Mexico, starting at Henderson Point in Pass Christian and finishing in Biloxi. The course is known for its breathtaking sunrise views over the water, offering runners a serene yet energizing start to race day. While the route remains mostly flat, the final stretch surprises many participants with a challenging incline on an overpass ramp before descending into the finish line inside Keesler Federal Park. The event is a highlight for coastal running enthusiasts, combining smooth race-day logistics with ample aid stations and an energetic post-race festival featuring local food, cold beer, and a jumbotron replaying finish-line moments.
Mississippi Blues Marathon
Jackson | Feb 22, 2025
Course Type: Rolling Hills
Elevation Gain: 1193 feet (363m)
Participants: 139 Finishers
Price: $115
The Mississippi Blues Marathon is a moving tribute to the Deep South’s rich musical and cultural history. Starting and finishing at the Mississippi State Capitol, runners take on a course that winds through Jackson’s vibrant neighborhoods, past historic landmarks like the Mississippi Supreme Court and the lush green spaces surrounding the capitol. But the real soul of this race lies in its connection to the blues. Along the route, runners are treated to the sounds of live blues music, honoring legends like B.B. King, whose 100th birthday will be celebrated at the 2025 event. Finishers receive a commemorative medal featuring King’s legacy, while special centennial cupcakes pay tribute to both King and civil rights icon Medgar Evers. From the challenging hills to the post-race jambalaya, every detail of this marathon reflects the heart and soul of Mississippi.
Mississippi River Marathon
Greenville | Feb 1, 2025
Course Type: Mostly Flat
Elevation Gain: 217 feet (66m)
Participants: 107 Finishers
Price: $95-$125
Spanning two states and crossing the iconic Greenville Bridge, the Mississippi River Marathon blends fast times with unforgettable scenery. Runners begin their journey in Lake Village, Arkansas, before making their way over the Mississippi River on Highway 82 -the only elevation change in an otherwise flat, speedy course. As the #1 fastest marathon in Mississippi, it’s a top pick for those chasing a Boston Marathon qualifying time. Race-day conditions are often ideal, with cool temperatures and low humidity helping runners stay strong to the finish in downtown Greenville. Along the way, well-placed aid stations every 1.5 to 2 miles offer hydration, GU gels, and medical support, ensuring a smooth race experience.
Tupelo Marathon
Tupelo | Aug 31, 2025
Course Type: Rolling Hills
Elevation Gain: 857 feet (261m)
Participants: 88 Finishers
Price: $70-$150
The Tupelo Marathon typical big-city race – it’s a gritty, no-frills challenge that stays true to the old-school marathon spirit. Runners take on gently rolling hills along quiet country roads, with little more than the hum of crickets and the occasional passing car for company. With an ultra-early 5:00 AM start, the first stretch is run in total darkness – you’ll learn the value of a headlamp to navigate the dimly lit roads. Despite the limited crowd support, the volunteers at water stations go above and beyond, offering encouragement and much-needed hydration in the heavy Mississippi humidity. The race’s signature tie-dye long-sleeve hoodie and skull-themed medal are a hit among finishers, making this a bucket-list event for those seeking a challenging marathon experience. And if you’re a fan of post-race swag, don’t forget to grab the Tupelo race sticker – finishers like to turn it into a magnet as a badge of honor for surviving the heat.
Run the Rainbow for Children’s
Jackson | Mar 15, 2025
Course Type: Rolling Hills
Participants: 65 Finishers
Price: $85
Run the Rainbow for Children’s blends Southern charm with a deep sense of purpose, offering runners a scenic tour of Jackson with heart. Starting at the lively Hal & Mal’s, a Jackson institution known for its soulful atmosphere, runners set off on a course that winds through the city. The rolling hills of Belhaven test endurance, while the stretches through Eastover offer a glimpse of Jackson’s tree-lined beauty. But it’s the pass through the University of Mississippi Medical Center campus that delivers the most powerful moment – you’ll stride past the Kathy and Joe Sanderson Tower, the only medical facility in the state dedicated solely to children, where families find hope. The energy of the St. Paddy’s celebration fuels the final miles, leading back to an unforgettable after-party filled with music, camaraderie, and a well-earned celebration of the cause that makes every step worthwhile.
Why Mississippi Marathons Are Worth Running
Mississippi may not be the first state that comes to mind when thinking about marathons, but its races offer a challenge and charm you won’t find anywhere else.
The courses are often hilly, making for a rewarding run that tests both endurance and strategy.
Many routes wind through historic districts, college campuses, and even along stretches of quiet countryside, giving runners a mix of city energy and peaceful scenery.
While some races are still growing, they make up for their size with passionate volunteers, well-supported aid stations, and a strong sense of community.
Plus, with events like Run the Rainbow for Children’s, you’re not just running for yourself – you’re running to make a difference.
Tips for Running a Marathon in Mississippi
Because Mississippi’s races can be hilly, train with elevation in mind. If you’re used to flat courses, adding hill repeats and strength training will help you power through.
Be prepared for changing weather – March races can bring anything from crisp mornings to warm, humid finishes, so layering is key.
Some courses, especially those that pass through highways or major intersections, may have minimal crowd support, so a strong mental game is essential.
Many races offer generous post-race celebrations, so plan to stick around and enjoy the local hospitality – whether it’s live music, Southern comfort food, or a well-earned drink at the after-party.
Conclusion
Mississippi offers marathons for every type of runner, from those seeking a fast PR to those who enjoy a scenic, laid-back race.
Whether you’re drawn to the coastal beauty of the Mississippi Gulf Coast Marathon or the musical energy of the Mississippi Blues Marathon, there’s a race to suit your goals.
Pick your event, train well, and enjoy the journey!
Row Brown is the founder of Refresh Row. He is a keen marathon runner, his favorite being the London Marathon. He’s now set himself the mission of Running the Entire Length of Spain, which is scheduled for late 2024.
